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AI HERONTWERPT NOBEL-WINNENDE EIWITTEN OM CELVEROUDING TE TERUG TE DRAAIEN
OpenAI, in samenwerking met de levensduur-startup Retro Bio, heeft een gespecialiseerd model ontwikkeld genaamd GPT-4b Micro dat de Nobelprijs-winnende Yamanaka-factoren met verbluffende efficiëntie heeft herontworpen.
In tegenstelling tot de ontdekking uit 2012 die minder dan 0,1% van de cellen over weken herprogrammeerde, hebben de door AI ontworpen eiwitten meer dan 30% van de cellen omgezet en krachtige DNA-schadeherstel aangetoond.
Meerdere laboratoria hebben de resultaten bevestigd over verschillende celtypen en aflevermethoden.
De doorbraak betekent een sprongetje voor regeneratieve geneeskunde, waarbij decennia van verouderingsonderzoek in slechts enkele weken worden samengeperst.
Bron: rowancheung
31 jan 2025
🚨 AI DID IN SECONDS WHAT NATURE NEEDED 500 MILLION YEARS FOR
Nature spent half a billion years crafting proteins—AI just did it in months. Meet ESM3, the super-powered AI that designs brand-new proteins from scratch, no evolution required.
This could change medicine, biotech, and maybe even life itself.
Trained on 2.78 billion proteins, ESM3 has 98 billion parameters, making it one of the most advanced AI models ever.
Instead of just remixing nature’s greatest hits, it creates entirely new proteins, like a biological DJ with infinite samples.
Its biggest flex?
esmGFP, a glowing protein 58% different from anything found in nature. Evolution would need millions of years to make this—ESM3 whipped it up in no time.
This isn’t just a cool science trick. It could revolutionize drug discovery, speed up new medicine development, and push biotech into sci-fi territory with stronger materials, cleaner energy, and futuristic food production.
It might even help us predict how life itself will evolve, which sounds like something we should keep an eye on.
AI-powered protein design isn’t just coming—it’s here. And it’s about to shake things up.
Source: bioRxiv
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